Assays

Please see our latest press release to the 25th anniversary of BioGenes!

Custom Synthesis of Standard and Challenging Modified Peptides

BioGenes’ range of services includes epitope prediction and peptide design as well as custom synthesis of standard and challenging modified peptides. The synthesis service will be performed with Biosyntan GmbH, our long-term partner with excellent expertise in synthesis of linear and cyclic peptides.

Our service includes:

Peptide design

  • Starting with a protein sequence, we support you in choosing the suitable peptide for producing antibodies. 

Automated, multiple solid-phase peptide synthesis

  • Chain length up to 100 residues in a scale of 1 to 500 mg,
  •  Purification by preparative HPLC (standard purity: 80% or 95%),
  • Analysis of all products by HPLC and mass spectrometry

Synthesis and modification of peptides

  • Modified peptides, e. g. phosphorylation, glycosylation
  • Fluorescently labelled peptides – NEW: Rhodamine 110 Protease Substrates
  • Histone and cell-penetrating peptides
  • N-and C-terminal derivatisation, biotinylation
  • Peptide thioesters for chemical ligation
  • Conjugation of peptides with proteins

Fluorescence Labelling

  • Fluorescein-, rhodamine-, cyanine- and coumarin-derivatives
  • Single isomer DYOMICS-label (spectral range 400-800 nm)
  • FRET-systems
  • Protease substrates (caspases, beta-secretase, and others):
    • with AMC or AFC or  with rhodamine 110 (Rh110)
      symmetric: (peptide)2-Rh110 or
      asymmetric: peptide-Rh110-X (X = D-Pro or gamma-Glu) 

NEW: Fluorescently labelled ubiquitin derivatives
(purity: 95% (HPLC), chemically synthesised)
e.g.    Ubiquitin(1-76)-Rh110-D-Pro or Ubiquitin(1-76)-AMC

Please download the flyer for more information.

If you have any questions or need a detailed quotation please contact us.

Contact

Michaela Grabo
+49 (0)30 65762395
Erik Tesch
+49 (0)30 65762402